Prioritization:String

From silico.biotoul.fr

Proximity measure

The proximity measure implemented is currently the following: a distance matrix is built consisting of all pairs shortest paths in the STRING graph. The proximity of a candidate gene to a set of genes is then computed as the average distance of the candidate gene to each known gene.

Data

STRING version 8.2 is currently in use for prioritization. The combined proteins associations scores have been filtered to keep only associations with a score of at least 600. The result is an unweighted undirected protein network.